ASTROCYTE-DERIVED GLUTATHIONE ATTENUATES HEMIN-INDUCED APOPTOSIS IN CEREBRAL MICROVASCULAR CELLS

Intracerebral hemorrhage (ICH) induces neurovascular injury via poorly defined mechanisms. The aim of the present study was to determine whether glio-vascular communication may restrict hemorrhagic vascular injury. Hemin, a hemoglobin by-product, concentration- and time-dependently increased apoptot...

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Detalhes bibliográficos
Main Authors: Sukumari-Ramesh, Sangeetha, Laird, Melissa D., Singh, Nagendra, Vender, John R., Alleyne, Cargill H., Dhandapani, Krishnan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951495/
https://ncbi.nlm.nih.gov/pubmed/20737478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21055
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