EFFECT OF DEEP HYPOTHERMIC CIRCULATORY ARREST FOLLOWED BY LOW FLOW CARDIOPULMONARY BYPASS ON BRAIN METABOLISM IN NEWBORN PIGLETS: COMPARISON OF PH-STAT AND ALPHA-STAT MANAGEMENT

OBJECTIVE: To compare the effects of pH-stat and alpha-stat management prior to deep hypothermic circulatory arrest (DHCA) followed by a period of low flow (two rates) cardiopulmonary bypass (CPB) on cortical oxygenation and selected regulatory proteins: Bax, Bcl-2, Caspase-3 and phospho-Akt. DESIGN...

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Main Authors: Pirzadeh, Afsaneh, Schears, Gregory, Pastuszko, Peter, Liu, Huiping, Kubin, Joanna, Reade, Erin, Mendoza-Paredes, Alberto, Greeley, William, Nadkarni, Vinay, Wilson, David F, Pastuszko, Anna
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951487/
https://ncbi.nlm.nih.gov/pubmed/20601925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0b013e3181e89e91
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