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Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
Leptin monotherapy reverses the deadly consequences and improves several of the metabolic imbalances caused by insulin-deficient type 1 diabetes (T1D) in rodents. However, the mechanism(s) underlying these effects is totally unknown. Here, we report that intracerebroventricular (icv) infusion of lep...
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| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951430/ https://ncbi.nlm.nih.gov/pubmed/20855609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008025107 |
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