Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis

Transforming growth factor-beta (TGF-β), a multifunctional cytokine regulating several immunologic processes, is expressed by virtually all cells as a biologically inactive molecule termed latent TGF-β (LTGF-β). We have previously shown that TGF-β activity increases during influenza virus infection...

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Autori principali: Carlson, Christina M., Turpin, Elizabeth A., Moser, Lindsey A., O'Brien, Kevin B., Cline, Troy D., Jones, Jeremy C., Tumpey, Terrence M., Katz, Jacqueline M., Kelley, Laura A., Gauldie, Jack, Schultz-Cherry, Stacey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951376/
https://ncbi.nlm.nih.gov/pubmed/20949074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001136
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