Inhibition of Plasmodium falciparum Field Isolates-Mediated Endothelial Cell Apoptosis by Fasudil: Therapeutic Implications for Severe Malaria

Plasmodium falciparum infection can abruptly progress to severe malaria, a life-threatening complication resulting from sequestration of parasitized red blood cells (PRBC) in the microvasculature of various organs such as the brain and lungs. PRBC adhesion can induce endothelial cell (EC) activation...

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Main Authors: Zang-Edou, Estelle S., Bisvigou, Ulrick, Taoufiq, Zacharie, Lékoulou, Faustin, Lékana-Douki, Jean Bernard, Traoré, Yves, Mazier, Dominique, Touré-Ndouo, Fousseyni S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951358/
https://ncbi.nlm.nih.gov/pubmed/20949056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013221
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