Characterization of LINE-1 Ribonucleoprotein Particles

The average human genome contains a small cohort of active L1 retrotransposons that encode two proteins (ORF1p and ORF2p) required for their mobility (i.e., retrotransposition). Prior studies demonstrated that human ORF1p, L1 RNA, and an ORF2p-encoded reverse transcriptase activity are present in ri...

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Autori principali: Doucet, Aurélien J., Hulme, Amy E., Sahinovic, Elodie, Kulpa, Deanna A., Moldovan, John B., Kopera, Huira C., Athanikar, Jyoti N., Hasnaoui, Manel, Bucheton, Alain, Moran, John V., Gilbert, Nicolas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951350/
https://ncbi.nlm.nih.gov/pubmed/20949108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001150
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