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Serum amyloid A (SAA3) produced by rabbit synovial fibroblasts treated with phorbol esters or interleukin 1 induces synthesis of collagenase and is neutralized with specific antiserum.

We report that nucleic acid sequence analysis of a full-length cDNA clone for a rabbit serum amyloid A (SAA)-like protein has identified this protein as more closely related to SAA3 than to SAA1. SAA3 induced collagenase synthesis in rabbit synovial fibroblasts, and immune IgG raised against this SA...

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Pubblicato in:J Clin Invest
Autori principali: Mitchell, T I, Coon, C I, Brinckerhoff, C E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1849144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115116
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