TNF/p38 alpha/Polycomb signalling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration

How regeneration cues are converted into the epigenetic information that controls gene expression in adult stem cells is currently unknown. We identified a novel inflammation-activated signalling in muscle stem (satellite) cells, by which the Polycomb Repressive Complex 2 (PRC2) represses Pax7 expre...

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Detalhes bibliográficos
Main Authors: Palacios, Daniela, Mozzetta, Chiara, Consalvi, Silvia, Caretti, Giuseppina, Saccone, Valentina, Proserpio, Valentina, Marquez, Victor E., Valente, Sergio, Mai, Antonello, Forcales, Sonia V., Sartorelli, Vittorio, Puri, Pier Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951277/
https://ncbi.nlm.nih.gov/pubmed/20887952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.08.013
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