TNF/p38 alpha/Polycomb signalling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration

How regeneration cues are converted into the epigenetic information that controls gene expression in adult stem cells is currently unknown. We identified a novel inflammation-activated signalling in muscle stem (satellite) cells, by which the Polycomb Repressive Complex 2 (PRC2) represses Pax7 expre...

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Hlavní autoři: Palacios, Daniela, Mozzetta, Chiara, Consalvi, Silvia, Caretti, Giuseppina, Saccone, Valentina, Proserpio, Valentina, Marquez, Victor E., Valente, Sergio, Mai, Antonello, Forcales, Sonia V., Sartorelli, Vittorio, Puri, Pier Lorenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951277/
https://ncbi.nlm.nih.gov/pubmed/20887952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.08.013
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