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RNA-Guided RNA Cleavage by a CRISPR RNA-Cas Protein Complex

Compelling evidence indicates that the CRISPR-Cas system protects prokaryotes from viruses and other potential genome invaders. This adaptive prokaryotic immune system arises from the clustered regularly interspaced short palindromic repeats (CRISPRs) found in prokaryotic genomes, which harbor short...

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Bibliographic Details
Main Authors: Hale, Caryn R., Zhao, Peng, Olson, Sara, Duff, Michael O., Graveley, Brenton R., Wells, Lance, Terns, Rebecca M., Terns, Michael P.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951265/
https://ncbi.nlm.nih.gov/pubmed/19945378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.040
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