Failure to Process Dentin Matrix Protein 1 (DMP1) into Fragments Leads to Its Loss of Function in Osteogenesis

Dentin matrix protein 1 (DMP1), an acidic protein important to the formation of bone and dentin, primarily exists as the processed NH(2)-terminal and COOH-terminal fragments in the extracellular matrix of the two tissues. Previous in vitro studies showed that the substitution of residue Asp(213) by...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Sun, Yao, Prasad, Monica, Gao, Tian, Wang, Xiaofang, Zhu, Qinglin, D'Souza, Rena, Feng, Jian Q., Qin, Chunlin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951243/
https://ncbi.nlm.nih.gov/pubmed/20663874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137059
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk