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NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C Virus
The small membrane protein p7 of hepatitis C virus forms oligomers and exhibits ion channel activity essential for virus infectivity. These viroporin features render p7 an attractive target for antiviral drug development. In this study, p7 from strain HCV-J (genotype 1b) was chemically synthesized a...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951219/ https://ncbi.nlm.nih.gov/pubmed/20667830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.122895 |
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