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Proinflammatory Cytokines Enhance Estrogen-dependent Expression of the Multidrug Transporter Gene ABCG2 through Estrogen Receptor and NFκB Cooperativity at Adjacent Response Elements

Constitutive activation of NFκB in estrogen receptor (ER)-positive breast cancer is associated with tumor recurrence and development of anti-estrogen resistance. Furthermore, a gene expression signature containing common targets for ER and NFκB has been identified and found to be associated with the...

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Detalhes bibliográficos
Main Authors: Pradhan, Madhumita, Bembinster, Leslie A., Baumgarten, Sarah C., Frasor, Jonna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951183/
https://ncbi.nlm.nih.gov/pubmed/20705611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155309
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