Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.

Oxidatively modified low density lipoprotein (LDL) exhibits several potentially atherogenic properties, and inhibition of LDL oxidation in rabbits decreases the rate of the development of atherosclerotic lesions. In vitro studies have suggested that cellular lipoxygenases may be involved in LDL oxid...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Ylä-Herttuala, S, Rosenfeld, M E, Parthasarathy, S, Sigal, E, Särkioja, T, Witztum, J L, Steinberg, D
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1991
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295117/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2010531/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115111
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