Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.

The human hepatoma cell line, HepG2, secreted an activity that degrades platelet-activating factor (PAF) by the hydrolysis of the sn-2 acetyl group. This activity was Ca++ independent, inhibited by diisopropylfluorophosphate but not by p-bromophenacyl bromide, and resistant to treatment with trypsin...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Satoh, K, Imaizumi, T, Kawamura, Y, Yoshida, H, Hiramoto, M, Takamatsu, S, Takamatsu, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115020
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