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Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

Nitric oxide (an endothelium-derived relaxing factor) induces smooth muscle relaxation and is an important mediator in the regulation of vascular tone. Advanced glycosylation end products, the glucose-derived moieties that form nonenzymatically and accumulate on long-lived tissue proteins, have been...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Bucala, R, Tracey, K J, Cerami, A
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1991
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991829/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115014
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