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Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol
Wingless (Wnt) signaling pathway regulates a variety of cellular processes including proliferation, differentiation, survival, apoptosis and cell motility. Aberrant activation of Wnt/β-catenin pathway has been observed in approximately one-third of melanomas and this subset has very poor prognosis s...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950938/ https://ncbi.nlm.nih.gov/pubmed/20732907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq169 |
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