Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation.

In a baboon graft model of arterial intimal thickening, smooth muscle cells (SMC) have been observed to proliferate underneath an intact monolayer of endothelium and in the absence of platelet adherence. Because platelets are not present and therefore cannot be a major source of growth stimulus, we...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Golden, M A, Au, Y P, Kirkman, T R, Wilcox, J N, Raines, E W, Ross, R, Clowes, A W
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1825089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115011
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