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Structure of the cholera toxin secretion channel in its closed state

The type II secretion system (T2SS) is a macromolecular complex spanning the inner and outer membranes of Gram-negative bacteria. Remarkably, the T2SS secretes folded proteins including multimeric assemblies like cholera toxin and heat-labile enterotoxin from Vibrio cholerae and enterotoxigenic Esch...

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Bibliographic Details
Main Authors: Reichow, Steve L., Korotkov, Konstantin V., Hol, Wim G. J., Gonen, Tamir
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950906/
https://ncbi.nlm.nih.gov/pubmed/20852644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1910
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