Activation of the Reg family genes by pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse pancreas

We have recently reported that Pdx1-Cre-mediated whole pancreas inactivation of IGF-I gene [in pancreatic-specific IGF-I gene-deficient (PID) mice] results in increased β-cell mass and significant protection against both type 1 and type 2 diabetes. Because the phenotype is unlikely a direct conseque...

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Detaylı Bibliyografya
Asıl Yazarlar: Lu, Yarong, Ponton, André, Okamoto, Hiroshi, Takasawa, Shin, Herrera, Pedro L., Liu, Jun-Li
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950860/
https://ncbi.nlm.nih.gov/pubmed/16449294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00596.2005
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