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Profiling of Substrate Specificity of SARS-CoV 3CL(pro)

BACKGROUND: The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-coronavirus is required for autoprocessing of the polyprotein, and is a potential target for treating coronaviral infection. METHODOLOGY/PRINCIPAL FINDINGS: To obtain a thorough understanding of substrate specificity of...

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Autors principals: Chuck, Chi-Pang, Chong, Lin-Tat, Chen, Chao, Chow, Hak-Fun, Wan, David Chi-Cheong, Wong, Kam-Bo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950840/
https://ncbi.nlm.nih.gov/pubmed/20949131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013197
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