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Phosphotyrosine Signaling: Evolving a New Cellular Communication System

Tyrosine phosphorylation controls many cellular functions. Yet the three-part toolkit that regulates phosphotyrosine signaling -- tyrosine kinases, phosphotyrosine phosphatases, and Src Homology 2 (SH2) domains -- is a relatively new innovation. Genomic analyses reveal how this revolutionary signali...

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Detalhes bibliográficos
Main Authors: Lim, Wendell A., Pawson, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950826/
https://ncbi.nlm.nih.gov/pubmed/20813250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.08.023
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