Accurate Detection of Uniparental Disomy and Microdeletions by SNP Array Analysis in Myelodysplastic Syndromes with Normal Cytogenetics

Progress in the management of patients with myelodysplastic syndromes (MDS) has been hampered by the inability to detect cytogenetic abnormalities in 40-60% of cases. We prospectively analyzed matched pairs of bone marrow and buccal cell (normal) DNA samples from 51 MDS patients by single nucleotide...

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Detalhes bibliográficos
Main Authors: Heinrichs, Stefan, Kulkarni, Rima V., Bueso-Ramos, Carlos E., Levine, Ross L., Loh, Mignon L., Li, Cheng, Neuberg, Donna, Kornblau, Steven M., Issa, Jean-Pierre, Gilliland, D. Gary, Garcia-Manero, Guillermo, Kantarjian, Hagop M., Estey, Elihu H., Look, A. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950785/
https://ncbi.nlm.nih.gov/pubmed/19387468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.82
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