Accurate Detection of Uniparental Disomy and Microdeletions by SNP Array Analysis in Myelodysplastic Syndromes with Normal Cytogenetics

Progress in the management of patients with myelodysplastic syndromes (MDS) has been hampered by the inability to detect cytogenetic abnormalities in 40-60% of cases. We prospectively analyzed matched pairs of bone marrow and buccal cell (normal) DNA samples from 51 MDS patients by single nucleotide...

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Main Authors: Heinrichs, Stefan, Kulkarni, Rima V., Bueso-Ramos, Carlos E., Levine, Ross L., Loh, Mignon L., Li, Cheng, Neuberg, Donna, Kornblau, Steven M., Issa, Jean-Pierre, Gilliland, D. Gary, Garcia-Manero, Guillermo, Kantarjian, Hagop M., Estey, Elihu H., Look, A. Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950785/
https://ncbi.nlm.nih.gov/pubmed/19387468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.82
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