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The Chromodomains of the Chd1 Chromatin Remodeler Regulate DNA Access to the ATPase Motor
Chromatin remodelers are ATP-driven machines that assemble, slide, and remove nucleosomes from DNA, but how the ATPase motors of remodelers are regulated is poorly understood. Here we show that the double chromodomain unit of the Chd1 remodeler blocks DNA binding and activation of the ATPase motor i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950701/ https://ncbi.nlm.nih.gov/pubmed/20832723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.012 |
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