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Mucosal potassium efflux mediated via Kcnn4 channels provides the driving force for electrogenic anion secretion in colon

Intermediate conductance K(+) (Kcnn4) channels are present in both mucosal and serosal membranes of colon. However, only serosal Kcnn4 channels have been shown to be essential for agonist-induced (cAMP and Ca(2+)) anion secretion. The present study sought to determine whether mucosal Kcnn4 channels...

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Détails bibliographiques
Auteurs principaux: Nanda Kumar, N. S., Singh, Satish K., Rajendran, Vazhaikkurichi M.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950693/
https://ncbi.nlm.nih.gov/pubmed/20616305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00101.2010
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