Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Epidermal growth factor (EGF) is one of the most promising candidates in NEC prophylaxis. Autophagy regulates cell homeostasis, but uncontrolled activation of autophagy may lead to cellular injury. The aim was...

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Detalhes bibliográficos
Main Authors: Maynard, Andrew A., Dvorak, Katerina, Khailova, Ludmila, Dobrenen, Holly, Arganbright, Kelly M., Halpern, Melissa D., Kurundkar, Ashish R., Maheshwari, Akhil, Dvorak, Bohuslav
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950687/
https://ncbi.nlm.nih.gov/pubmed/20539009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00076.2010
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