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Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Epidermal growth factor (EGF) is one of the most promising candidates in NEC prophylaxis. Autophagy regulates cell homeostasis, but uncontrolled activation of autophagy may lead to cellular injury. The aim was...

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Autores principales: Maynard, Andrew A., Dvorak, Katerina, Khailova, Ludmila, Dobrenen, Holly, Arganbright, Kelly M., Halpern, Melissa D., Kurundkar, Ashish R., Maheshwari, Akhil, Dvorak, Bohuslav
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950687/
https://ncbi.nlm.nih.gov/pubmed/20539009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00076.2010
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