Chikungunya Virus Nonstructural Protein 2 Inhibits Type I/II Interferon-Stimulated JAK-STAT Signaling

Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected cells to respond to interferon (IFN). Recent res...

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Detalhes bibliográficos
Main Authors: Fros, Jelke J., Liu, Wen Jun, Prow, Natalie A., Geertsema, Corinne, Ligtenberg, Maarten, Vanlandingham, Dana L., Schnettler, Esther, Vlak, Just M., Suhrbier, Andreas, Khromykh, Alexander A., Pijlman, Gorben P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950581/
https://ncbi.nlm.nih.gov/pubmed/20686047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00949-10
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