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Simian Virus 40 Activates ATR-Δp53 Signaling To Override Cell Cycle and DNA Replication Control

During infection, simian virus 40 (SV40) attempts to take hold of the cell, while the host responds with various defense systems, including the ataxia-telangiectasia mutated/ATM-Rad3 related (ATM/ATR)-mediated DNA damage response pathways. Here we show that upon viral infection, ATR directly activat...

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Autori principali: Rohaly, Gabor, Korf, Katharina, Dehde, Silke, Dornreiter, Irena
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950571/
https://ncbi.nlm.nih.gov/pubmed/20686026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00122-10
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