The Glycosylated Gag Protein of a Murine Leukemia Virus Inhibits the Antiretroviral Function of APOBEC3

APOBEC proteins have evolved as innate defenses against retroviral infections. Human immunodeficiency virus (HIV) encodes the Vif protein to evade human APOBEC3G; however, mouse retroviruses do not encode a Vif homologue, and it has not been understood how they evade mouse APOBEC3. We report here a...

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Main Authors: Kolokithas, Angelo, Rosenke, Kyle, Malik, Frank, Hendrick, Duncan, Swanson, Lukas, Santiago, Mario L., Portis, John L., Hasenkrug, Kim J., Evans, Leonard H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950561/
https://ncbi.nlm.nih.gov/pubmed/20702647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01023-10
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