The Glycosylated Gag Protein of a Murine Leukemia Virus Inhibits the Antiretroviral Function of APOBEC3

APOBEC proteins have evolved as innate defenses against retroviral infections. Human immunodeficiency virus (HIV) encodes the Vif protein to evade human APOBEC3G; however, mouse retroviruses do not encode a Vif homologue, and it has not been understood how they evade mouse APOBEC3. We report here a...

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Hlavní autoři: Kolokithas, Angelo, Rosenke, Kyle, Malik, Frank, Hendrick, Duncan, Swanson, Lukas, Santiago, Mario L., Portis, John L., Hasenkrug, Kim J., Evans, Leonard H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950561/
https://ncbi.nlm.nih.gov/pubmed/20702647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01023-10
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