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Mononucleosis and Antigen-Driven T Cell Responses Have Different Requirements for Interleukin-2 Signaling in Murine Gammaherpesvirus Infection

Interleukin-2 (IL-2) has been implicated as being necessary for the optimal formation of primary CD8(+) T cell responses against various pathogens. Here we have examined the role that IL-2 signaling plays in several aspects of a CD8(+) T cell response against murine gammaherpesvirus 68 (MHV-68). Exp...

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Bibliografiske detaljer
Main Authors: Molloy, Michael, Zhang, Weijun, Usherwood, Edward
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950560/
https://ncbi.nlm.nih.gov/pubmed/20686022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00856-10
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