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CD69 Association with Jak3/Stat5 Proteins Regulates Th17 Cell Differentiation

T-cell differentiation involves the early decision to commit to a particular pattern of response to an antigen. Here, we show that the leukocyte activation antigen CD69 limits differentiation into proinflammatory helper T cells (Th17 cells). Upon antigen stimulation in vitro, CD4(+) T cells from CD6...

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Detalhes bibliográficos
Main Authors: Martín, Pilar, Gómez, Manuel, Lamana, Amalia, Cruz-Adalia, Arantxa, Ramírez-Huesca, Marta, Ursa, María Ángeles, Yáñez-Mo, María, Sánchez-Madrid, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950549/
https://ncbi.nlm.nih.gov/pubmed/20696842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00456-10
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