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Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability
Lysine-specific demethylase 1 (LSD1), which demethylates mono- and dimethylated histone H3-Lys4 as part of a complex including CoREST and histone deacetylases (HDACs), is essential for embryonic development in the mouse beyond embryonic day 6.5 (e6.5). To determine the role of LSD1 during this early...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950538/ https://ncbi.nlm.nih.gov/pubmed/20713442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00521-10 |
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