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Purine catabolism in polymorphonuclear neutrophils. Phorbol myristate acetate-induced accumulation of adenosine owing to inactivation of extracellularly released adenosine deaminase.

Since physiological concentrations (0.1-1 microM) of adenosine influence the functions of human polymorphonuclear neutrophils (PMNs), we investigated the metabolism of adenosine in suspensions of stimulated and unstimulated PMNs. Stimulation with phorbol myristate acetate (PMA, 1 microM), but not by...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: van Waeg, G, Van den Berghe, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1898656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114987
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