AmrZ Beta-Sheet Residues Are Essential for DNA Binding and Transcriptional Control of Pseudomonas aeruginosa Virulence Genes

AmrZ is a putative ribbon-helix-helix (RHH) transcriptional regulator. RHH proteins utilize residues within the β-sheet for DNA binding, while the α-helices promote oligomerization. AmrZ is of interest due to its dual roles as a transcriptional activator and as a repressor, regulating genes encoding...

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Hlavní autoři: Waligora, Elizabeth A., Ramsey, Deborah M., Pryor, Edward E., Lu, Haiping, Hollis, Thomas, Sloan, Gina P., Deora, Rajendar, Wozniak, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950516/
https://ncbi.nlm.nih.gov/pubmed/20709902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00711-10
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