Complex comprised of dextran magnetite and conjugated cisplatin exhibiting selective hyperthermic and controlled-release potential

We developed a dextran-magnetite conjugated cisplatin (DM-Cis) complex for use in thermal ablation and as a chemotherapeutic drug. To produce DM-Cis we reacted Cis with 1 mL DM (56 mg/mL iron). The temperature rise of DM-Cis was measured in vitro and in vivo under a portable induction-heating (IH) d...

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Autors principals: Sonoda, Akinaga, Nitta, Norihisa, Nitta-Seko, Ayumi, Ohta, Shinich, Takamatsu, Shigeyuki, Ikehata, Yoshio, Nagano, Isamu, Jo, Jun-ichiro, Tabata, Yasuhiko, Takahashi, Masashi, Matsui, Osamu, Murata, Kiyoshi
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2010
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950408/
https://ncbi.nlm.nih.gov/pubmed/20957172
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