Role of Interleukin-17A in Cell-Mediated Protection against Staphylococcus aureus Infection in Mice Immunized with the Fibrinogen-Binding Domain of Clumping Factor A

Clumping factor A (ClfA) is a fibrinogen-binding cell wall-attached protein and an important virulence factor of Staphylococcus aureus. Previous studies reported that an immunization with the fibrinogen-binding domain of ClfA (ClfA(40-559)) protected animals against S. aureus infection. It was repor...

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Bibliographic Details
Main Authors: Narita, Kouji, Hu, Dong-Liang, Mori, Fumiaki, Wakabayashi, Koichi, Iwakura, Yoichiro, Nakane, Akio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950370/
https://ncbi.nlm.nih.gov/pubmed/20679443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00447-10
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