Repertoire of HLA-DR1-Restricted CD4 T-Cell Responses to Capsular Caf1 Antigen of Yersinia pestis in Human Leukocyte Antigen Transgenic Mice

Yersinia pestis is the causative agent of plague, a rapidly fatal infectious disease that has not been eradicated worldwide. The capsular Caf1 protein of Y. pestis is a protective antigen under development as a recombinant vaccine. However, little is known about the specificity of human T-cell respo...

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Main Authors: Musson, Julie A., Ingram, Rebecca, Durand, Guillaume, Ascough, Stephanie, Waters, Emma L., Hartley, M. Gillian, Robson, Timothy, Maillere, Bernard, Williamson, E. Diane, Sriskandan, Shiranee, Altmann, Daniel, Robinson, John H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950366/
https://ncbi.nlm.nih.gov/pubmed/20660611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00195-10
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