Pic, an Autotransporter Protein Secreted by Different Pathogens in the Enterobacteriaceae Family, Is a Potent Mucus Secretagogue

A hallmark of enteroaggregative Escherichia coli (EAEC) infection is a formation of biofilm, which comprises a mucus layer with immersed bacteria in the intestines of patients. While studying the mucinolytic activity of Pic in an in vivo system, rat ileal loops, we surprisingly found that EAEC induc...

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Detalhes bibliográficos
Main Authors: Navarro-Garcia, Fernando, Gutierrez-Jimenez, Javier, Garcia-Tovar, Carlos, Castro, Luis A., Salazar-Gonzalez, Hector, Cordova, Vanessa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950354/
https://ncbi.nlm.nih.gov/pubmed/20696826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00523-10
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