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Mucosal Administration of Flagellin Protects Mice from Streptococcus pneumoniae Lung Infection

Streptococcus pneumoniae is a major cause of pneumonia in infants and the elderly. Innate defenses are essential to the control of pneumococcal infections, and deficient responses can trigger disease in susceptible individuals. Here we showed that flagellin can locally activate innate immunity and t...

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Autors principals: Muñoz, Natalia, Van Maele, Laurye, Marqués, Juan M., Rial, Analía, Sirard, Jean-Claude, Chabalgoity, José A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950348/
https://ncbi.nlm.nih.gov/pubmed/20643849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00224-10
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