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Enantioseparation of Lomefloxacin Hydrochloride by High-speed Counter-current Chromatography Using Sulfated-β-cyclodextrin as a Chiral Selector

Enantiomers of lomefloxacin hydrochloride were separated by high-speed counter-current chromatography using sulfated-β-cyclodextrin as a chiral selector (CS). The separation was performed with a two-phase solvent system composed of ethyl acetate-methanol-water (10:1:10, v/v) containing CS at 0~60 mm...

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Autores principales: Wei, Yun, Du, Shijuan, Ito, Yoichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950249/
https://ncbi.nlm.nih.gov/pubmed/20837406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.08.030
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