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Contrast-enhanced in vivo magnetic resonance microscopy of the mouse brain enabled by non-invasive opening of the blood-brain barrier with ultrasound

The use of contrast agents for neuroimaging is limited by the blood-brain barrier (BBB), which restricts entry into the brain. To administer imaging agents to the brain of rats, intracarotid infusions of hypertonic mannitol have been used to open the BBB. However, this technically challenging approa...

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Detalhes bibliográficos
Main Authors: Howles, Gabriel P., Bing, Kristin F., Qi, Yi, Rosenzweig, Stephen J., Nightingale, Kathryn R., Johnson, G. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950102/
https://ncbi.nlm.nih.gov/pubmed/20740666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22411
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