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Human γδ T lymphocytes for immunotherapeutic strategies against cancer

γδ T lymphocytes are a numerically small subset of T cells with potent cytotoxic activity against a variety of tumor cells. Human γδ T cells expressing the Vγ9Vδ2 T cell antigen receptor recognize endogenous pyrophosphate molecules that are overproduced in transformed cells. Moreover, the intracellu...

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Detalles Bibliográficos
Autor principal: Kabelitz, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: Medicine Reports Ltd 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950047/
https://ncbi.nlm.nih.gov/pubmed/20948839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/M2-45
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