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A mathematical model of the volume, pH, and ion content regulation in reticulocytes. Application to the pathophysiology of sickle cell dehydration.

We developed a mathematical model of the reticulocyte, seeking to explain how a cell with similar volume but much higher ionic traffic than the mature red cell (RBC) regulates its volume, pH, and ion content in physiological and abnormal conditions. Analysis of the fluxbalance required by reticulocy...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Lew, V L, Freeman, C J, Ortiz, O E, Bookchin, R M
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1991
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1985088/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114958
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