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Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: Genotype and phenotype analyses from a case-control study

Cell cycle checkpoints play critical roles in the maintenance of genomic integrity and inactivation of checkpoint genes, and are frequently perturbed in most cancers. In a case-control study of 299 non-small cell lung cancer cases and 550 controls in Maryland, we investigated the association between...

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Detalhes bibliográficos
Main Authors: Zheng, Yun-Ling, Kosti, Ourania, Loffredo, Christopher, Bowman, Elise, Mechanic, Leah, Perlmutter, Donna, Jones, Raymond, Shields, Peter G., Harris, Curtis
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950001/
https://ncbi.nlm.nih.gov/pubmed/19626602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24771
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