Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?

BACKGROUND: Cholesterol content of cerebral membranes is tightly regulated by elaborate mechanisms that balance the level of cholesterol synthesis, uptake and efflux. Among the conventional regulatory elements, a recent research focus has been nuclear receptors, a superfamily of ligand-activated tra...

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Bibliographic Details
Main Authors: Akram, Afia, Schmeidler, James, Katsel, Pavel, Hof, Patrick R, Haroutunian, Vahram
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949865/
https://ncbi.nlm.nih.gov/pubmed/20843353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-36
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