Identification of sequence polymorphism in the D-Loop region of mitochondrial DNA as a risk factor for hepatocellular carcinoma with distinct etiology

BACKGROUND: Hepatocellular carcinoma (HCC) is frequently preceded by hepatitis virus infection or alcohol abuse. Genetic backgrounds may increase susceptibility to HCC from these exposures. METHODS: Mitochondrial DNA (mtDNA) of peripheral blood, tumor, and/or adjacent non-tumor tissue from 49 hepati...

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Detalhes bibliográficos
Main Authors: Zhang, Ruixing, Zhang, Fengbin, Wang, Cuiju, Wang, Shunxiang, Shiao, Yih-Horng, Guo, Zhanjun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949825/
https://ncbi.nlm.nih.gov/pubmed/20849651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-130
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