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Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma

BACKGROUND: The canonical Wnt signaling is concurrently important for osteoblast differentiation and myeloma cell proliferation. Its activation in myeloma cells and its inhibition in osteoblasts and their progenitors have been identified in the previous studies. Osteoblast progenitors and myeloma ce...

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Main Authors: Dun, Xiaoyi, Jiang, Hua, Zou, Jianfeng, Shi, Jun, Zhou, Lili, Zhu, Rong, Hou, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949801/
https://ncbi.nlm.nih.gov/pubmed/20846389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-247
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