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Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo

INTRODUCTION: Triple-negative breast cancer does not express estrogen and progesterone receptors, and no overexpression/amplification of the HER2-neu gene occurs. Therefore, this subtype of breast cancer lacks the benefits of specific therapies that target these receptors. Today chemotherapy is the...

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Autori principali: Gründker, Carsten, Föst, Crispin, Fister, Stefanie, Nolte, Nadine, Günthert, Andreas R, Emons, Günter
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949636/
https://ncbi.nlm.nih.gov/pubmed/20630060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2606
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