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Tumor senescence and radioresistant tumor-initiating cells (TICs): let sleeping dogs lie!

Preclinical data from cell lines and experimental tumors support the concept that breast cancer-derived tumor-initiating cells (TICs) are relatively resistant to ionizing radiation and chemotherapy. This could be a major determinant of tumor recurrence following treatment. Increased clonogenic survi...

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Autori principali: Zafarana, Gaetano, Bristow, Robert G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949629/
https://ncbi.nlm.nih.gov/pubmed/20619004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2597
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