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FGF receptors 1 and 2 control chemically-induced injury and compound detoxification in regenerating livers of mice

BACKGROUND & AIMS: Fibroblast growth factor receptor (FGFR) 4 controls bile acid metabolism and protects the liver from fibrosis, but the roles of FGFR1 and FGFR2 in the adult liver are largely unknown. We investigated the functions and mechanisms of action of these receptors in liver homeostasi...

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Main Authors: Böhm, Friederike, Speicher, Tobias, Hellerbrand, Claus, Dickson, Clive, Partanen, Juha M., Ornitz, David M., Werner, Sabine
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949525/
https://ncbi.nlm.nih.gov/pubmed/20603121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.06.069
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