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Molecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif
The HIV-1 Virion infectivity factor (Vif) inhibits the innate viral immunity afforded by the APOBEC3 family of cytidine deaminases. Vif targets the APOBEC3 family for poly-ubiquitination and subsequent proteasomal degradation by linking the Elongin BC dependent ubiquitin ligase complex with the APOB...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949506/ https://ncbi.nlm.nih.gov/pubmed/20728451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.026 |
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